mox·ie (mŏk’sē)

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mox·ie (mŏk’sē) noun.

  1. Skill; know-how.
  2. Courage.
  3. Aggressive energy; initiative.

Popularized by MoxieTM registered in 1924 for a bitter soft drink; the word was used as far back as 1876 as the name of a patent medicine advertised to “build up your nerve.”  The exact origins of the word is unknown.